Rxcurve
Biosimilars · Eculizumab

Epysqli is paid 27.9% below Soliris

2 biosimilars bill against Soliris (J1299). On average they are paid ↓ 17.8% relative to the reference product per 2 MG in 4Q26.

  • Soliris (reference)
  • Epysqli
  • Bkemv
Payment limit per 2 MG, last 8 quarters. Reference product as the thick navy line, biosimilars in teal and other colors.

All products

ProductCodeCMS descriptionPer 2 MGvs. referenceCMS 8% add-on note8 quarters
Soliris J1299 Inj, eculizumab, 2 mg $43.763 Reference –
Epysqli Q5151 Inj, eculizumab-aagh, 2 mg $31.547 ↓ 27.9% Yes
Bkemv Q5152 Inj, eculizumab-aeeb, 2 mg $40.412 ↓ 7.7% Yes

Payment limits are from the CMS 4Q26 file. Which products are grouped together comes from the site’s biosimilar groups list (reference/biosimilar_groups/2026-10-17T183707Z_d3109bb50c53.csv), checked by hand; it is not a CMS file. “CMS 8% add-on note” shows whether CMS’s notes say the 8% of reference product add-on was applied.