Epysqli is paid 27.9% below Soliris
2 biosimilars bill against Soliris (J1299). On average they are paid ↓ 17.8% relative to the reference product per 2 MG in 4Q26.
- Soliris (reference)
- Epysqli
- Bkemv
AfliberceptBevacizumabDenosumabEculizumabEpoetin alfaFilgrastimInfliximabNatalizumabPegfilgrastimRanibizumabRituximabTocilizumabTrastuzumabUstekinumab
2 biosimilars bill against Soliris (J1299). On average they are paid ↓ 17.8% relative to the reference product per 2 MG in 4Q26.
| Product | Code | CMS description | Per 2 MG | vs. reference | CMS 8% add-on note | 8 quarters |
|---|---|---|---|---|---|---|
| Soliris | J1299 | Inj, eculizumab, 2 mg | $43.763 | Reference | – | |
| Epysqli | Q5151 | Inj, eculizumab-aagh, 2 mg | $31.547 | ↓ 27.9% | Yes | |
| Bkemv | Q5152 | Inj, eculizumab-aeeb, 2 mg | $40.412 | ↓ 7.7% | Yes |
Payment limits are from the CMS 4Q26 file. Which products are grouped together comes from the site’s biosimilar groups list (reference/biosimilar_groups/2026-10-17T183707Z_d3109bb50c53.csv), checked by hand; it is not a CMS file. “CMS 8% add-on note” shows whether CMS’s notes say the 8% of reference product add-on was applied.