Methotrexate oral 2.5 mg
Products billed under this code include Methotrexate, Trexall.
Payment limit per 2.5 MG, by effective quarter, 1Q21 to 4Q26. Gaps mean the code was not in that quarter’s file, or CMS gave no payment limit.Products billed under J8610
From the 4Q26 NDC–HCPCS crosswalk. “Limit / pkg” is the 4Q26 payment limit times the billing units in one package.
| Product | Labeler | NDC | Units / pkg | Limit / pkg |
|---|---|---|---|---|
| Methotrexate | Hikma Pharmaceuticals USA Inc. | 00054-4550-25 | 100 | $15.70 |
| Methotrexate | Hikma Pharmaceuticals USA Inc. | 00054-8550-25 | 100 | $15.70 |
| Methotrexate | Mylan Pharmaceuticals Inc. | 00378-0014-01 | 100 | $15.70 |
| Methotrexate | Barr Pharmaceuticals, Inc. | 00555-0572-02 | 100 | $15.70 |
| Methotrexate | Barr Pharmaceuticals, Inc. | 00555-0572-35 | 36 | $5.652 |
| Methotrexate | Major Pharmaceuticals | 00904-7141-10 | 20 | $3.14 |
| Methotrexate | Accord Healthcare Inc | 16729-0486-01 | 100 | $15.70 |
| Methotrexate | Sun Pharmaceutical Global FZE. | 47335-0235-83 | 100 | $15.70 |
| Methotrexate | Sun Pharmaceutical Global FZE. | 47335-0235-96 | 36 | $5.652 |
| Methotrexate | A-S Medication Solutions | 50090-3418-09 | 36 | $5.652 |
Show all 20 products
| Product | Labeler | NDC | Units / pkg | Limit / pkg |
|---|---|---|---|---|
| Methotrexate | A-S Medication Solutions | 50090-5457-02 | 100 | $15.70 |
| Methotrexate | A-S Medication Solutions | 50090-5457-09 | 36 | $5.652 |
| Methotrexate | AvPAK | 50268-0527-15 | 50 | $7.85 |
| Methotrexate | Mylan Institutional Inc. | 51079-0670-05 | 20 | $3.14 |
| Methotrexate | Aurobindo Pharma USA, Inc. | 59651-0182-01 | 100 | $15.70 |
| Methotrexate | Chartwell | 62135-0772-35 | 36 | $5.652 |
| Trexall | Teva Women's Health LLC | 51285-0366-01 | 60 | $9.42 |
| Trexall | Teva Women's Health LLC | 51285-0367-01 | 90 | $14.13 |
| Trexall | Teva Women's Health LLC | 51285-0368-01 | 120 | $18.84 |
| Trexall | Teva Women's Health LLC | 51285-0369-01 | 180 | $28.26 |
Every quarter
| Quarter | Payment limit | Change | Billing unit | Description | Source file |
|---|---|---|---|---|---|
| 4Q26 | $0.157 | +$0.003 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted September 17, 2026 |
| 3Q26 | $0.154 | +$0.014 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted September 15, 2026 |
| 2Q26 | $0.14 | −$0.011 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted September 15, 2026 |
| 1Q26 | $0.151 | −$0.038 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted September 15, 2026 |
| 4Q25 | $0.189 | −$0.009 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted September 8, 2026 |
| 3Q25 | $0.198 | −$0.003 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted March 10, 2026 |
| 2Q25 | $0.201 | +$0.024 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted March 10, 2026 |
| 1Q25 | $0.177 | −$0.047 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted December 19, 2025 |
| 4Q24 | $0.224 | −$0.015 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted June 11, 2025 |
| 3Q24 | $0.239 | −$0.004 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted June 11, 2025 |
| 2Q24 | $0.243 | −$0.024 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted March 11, 2025 |
| 1Q24 | $0.267 | +$0.012 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted December 19, 2024 |
| 4Q23 | $0.255 | +$0.023 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted October 10, 2024 |
| 3Q23 | $0.232 | −$0.163 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted June 5, 2024 |
| 2Q23 | $0.395 | +$0.169 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted February 23, 2024 |
| 1Q23 | $0.226 | −$0.016 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted December 6, 2023 |
| 4Q22 | $0.242 | +$0.055 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted June 22, 2023 |
| 3Q22 | $0.187 | −$0.028 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted June 9, 2023 |
| 2Q22 | $0.215 | +$0.019 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted December 14, 2022 |
| 1Q22 | $0.196 | −$0.219 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted June 8, 2022 |
| 4Q21 | $0.415 | +$0.042 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted June 2, 2022 |
| 3Q21 | $0.373 | +$0.151 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted June 2, 2022 |
| 2Q21 | $0.222 | +$0.08 | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted March 1, 2022 |
| 1Q21 | $0.142 | – | 2.5 MG | Methotrexate oral 2.5 mg | v1, posted December 10, 2021 |
“Change” is the difference from the previous quarter, shown only when both quarters have a payment limit and the billing unit is the same. “vs. last quarter” and “vs. a year ago” follow the same rule.
CMS source files
- 4Q26: 2026-09-17_october-2026-medicare-part-b-payment-limit-files-final.zipposted September 17, 2026
- 4Q26: 2026-09-17_october-2026-ndc-hcpcs-crosswalk-final.zipposted September 17, 2026
- 3Q26: 2026-09-15_july-2026-medicare-part-b-payment-limit-files.zipposted September 15, 2026
- 2Q26: 2026-09-15_april-2026-medicare-part-b-payment-limit-files-final-file.zipposted September 15, 2026
- 1Q26: 2026-09-15_january-2026-medicare-part-b-payment-limit-files.zipposted September 15, 2026
- 4Q25: 2026-09-08_october-2025-asp-pricing-final-file.zipposted September 8, 2026
- 3Q25: 2026-03-10_july-2025-asp-pricing-file.zipposted March 10, 2026
- 2Q25: 2026-03-10_april-2025-asp-pricing-file.zipposted March 10, 2026
- 1Q25: 2025-12-19_january-2025-asp-pricing-file-03-11-25-final-file.zipposted December 19, 2025
- 4Q24: 2025-06-11_october-2024-asp-pricing-file.zipposted June 11, 2025
- 3Q24: 2025-06-11_july-2024-asp-pricing-file.zipposted June 11, 2025
- 2Q24: 2025-03-11_april-2024-asp-pricing-file.zipposted March 11, 2025
- 1Q24: 2024-12-19_january-2024-asp-pricing-file.zipposted December 19, 2024
- 4Q23: 2024-10-10_october-2023-asp-pricing-file.zipposted October 10, 2024
- 3Q23: 2024-06-05_july-2023-asp-pricing-file.zipposted June 5, 2024
- 2Q23: 2024-02-23_april-2023-asp-pricing-file.zipposted February 23, 2024
- 1Q23: 2023-12-06_january-2023-asp-pricing-file.zipposted December 6, 2023
- 4Q22: 2023-06-22_october-2022-asp-pricing-file.zipposted June 22, 2023
- 3Q22: 2023-06-09_july-2022-asp-pricing-file.zipposted June 9, 2023
- 2Q22: 2022-12-14_april-2022-asp-pricing-file.zipposted December 14, 2022
- 1Q22: 2022-06-08_january-2022-asp-pricing-file.zipposted June 8, 2022
- 4Q21: 2022-06-02_october-2021-asp-pricing-file.zipposted June 2, 2022
- 3Q21: 2022-06-02_july-2021-asp-pricing-file.zipposted June 2, 2022
- 2Q21: 2022-03-01_april-2021-asp-pricing-file.zipposted March 1, 2022
- 1Q21: 2021-12-10_january-2021-asp-pricing-file.zipposted December 10, 2021