Hyaluronidase recombinant
Products billed under this code include Hylenex.
Payment limit per 1 USP UNIT, by effective quarter, 1Q21 to 4Q26. Gaps mean the code was not in that quarter’s file, or CMS gave no payment limit.Products billed under J3473
From the 4Q26 NDC–HCPCS crosswalk. “Limit / pkg” is the 4Q26 payment limit times the billing units in one package.
| Product | Labeler | NDC | Units / pkg | Limit / pkg |
|---|---|---|---|---|
| Hylenex | Antares Pharma, Inc. | 18657-0117-04 | 600 | $218.40 |
| Hylenex | HF Acquisition Co. LLC, DBA HealthFirst | 51662-1555-01 | 150 | $54.60 |
Every quarter
| Quarter | Payment limit | Change | Billing unit | Description | Source file |
|---|---|---|---|---|---|
| 4Q26 | $0.364 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted September 17, 2026 |
| 3Q26 | $0.364 | +$0.001 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted September 15, 2026 |
| 2Q26 | $0.363 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted September 15, 2026 |
| 1Q26 | $0.363 | +$0.001 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted September 15, 2026 |
| 4Q25 | $0.362 | −$0.001 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted September 8, 2026 |
| 3Q25 | $0.363 | −$0.001 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted March 10, 2026 |
| 2Q25 | $0.364 | −$0.001 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted March 10, 2026 |
| 1Q25 | $0.365 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted December 19, 2025 |
| 4Q24 | $0.365 | +$0.002 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted June 11, 2025 |
| 3Q24 | $0.363 | +$0.002 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted June 11, 2025 |
| 2Q24 | $0.361 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted March 11, 2025 |
| 1Q24 | $0.361 | +$0.002 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted December 19, 2024 |
| 4Q23 | $0.359 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted October 10, 2024 |
| 3Q23 | $0.359 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted June 5, 2024 |
| 2Q23 | $0.359 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted February 23, 2024 |
| 1Q23 | $0.359 | −$0.001 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted December 6, 2023 |
| 4Q22 | $0.36 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted June 22, 2023 |
| 3Q22 | $0.36 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted June 9, 2023 |
| 2Q22 | $0.36 | −$0.001 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted December 14, 2022 |
| 1Q22 | $0.361 | +$0.001 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted June 8, 2022 |
| 4Q21 | $0.36 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted June 2, 2022 |
| 3Q21 | $0.36 | +$0.001 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted June 2, 2022 |
| 2Q21 | $0.359 | $0.00 | 1 USP UNIT | Hyaluronidase recombinant | v1, posted March 1, 2022 |
| 1Q21 | $0.359 | – | 1 USP UNIT | Hyaluronidase recombinant | v1, posted December 10, 2021 |
“Change” is the difference from the previous quarter, shown only when both quarters have a payment limit and the billing unit is the same. “vs. last quarter” and “vs. a year ago” follow the same rule.
CMS source files
- 4Q26: 2026-09-17_october-2026-medicare-part-b-payment-limit-files-final.zipposted September 17, 2026
- 4Q26: 2026-09-17_october-2026-ndc-hcpcs-crosswalk-final.zipposted September 17, 2026
- 3Q26: 2026-09-15_july-2026-medicare-part-b-payment-limit-files.zipposted September 15, 2026
- 2Q26: 2026-09-15_april-2026-medicare-part-b-payment-limit-files-final-file.zipposted September 15, 2026
- 1Q26: 2026-09-15_january-2026-medicare-part-b-payment-limit-files.zipposted September 15, 2026
- 4Q25: 2026-09-08_october-2025-asp-pricing-final-file.zipposted September 8, 2026
- 3Q25: 2026-03-10_july-2025-asp-pricing-file.zipposted March 10, 2026
- 2Q25: 2026-03-10_april-2025-asp-pricing-file.zipposted March 10, 2026
- 1Q25: 2025-12-19_january-2025-asp-pricing-file-03-11-25-final-file.zipposted December 19, 2025
- 4Q24: 2025-06-11_october-2024-asp-pricing-file.zipposted June 11, 2025
- 3Q24: 2025-06-11_july-2024-asp-pricing-file.zipposted June 11, 2025
- 2Q24: 2025-03-11_april-2024-asp-pricing-file.zipposted March 11, 2025
- 1Q24: 2024-12-19_january-2024-asp-pricing-file.zipposted December 19, 2024
- 4Q23: 2024-10-10_october-2023-asp-pricing-file.zipposted October 10, 2024
- 3Q23: 2024-06-05_july-2023-asp-pricing-file.zipposted June 5, 2024
- 2Q23: 2024-02-23_april-2023-asp-pricing-file.zipposted February 23, 2024
- 1Q23: 2023-12-06_january-2023-asp-pricing-file.zipposted December 6, 2023
- 4Q22: 2023-06-22_october-2022-asp-pricing-file.zipposted June 22, 2023
- 3Q22: 2023-06-09_july-2022-asp-pricing-file.zipposted June 9, 2023
- 2Q22: 2022-12-14_april-2022-asp-pricing-file.zipposted December 14, 2022
- 1Q22: 2022-06-08_january-2022-asp-pricing-file.zipposted June 8, 2022
- 4Q21: 2022-06-02_october-2021-asp-pricing-file.zipposted June 2, 2022
- 3Q21: 2022-06-02_july-2021-asp-pricing-file.zipposted June 2, 2022
- 2Q21: 2022-03-01_april-2021-asp-pricing-file.zipposted March 1, 2022
- 1Q21: 2021-12-10_january-2021-asp-pricing-file.zipposted December 10, 2021