Products billed under this code include Piperacillin And Tazobactam, Piperacillin Sodium-Tazobactam Sodium, Piperacillin Sodium/Tazobactam Sodium, Zosyn.
Payment limit per 1.125 GM, by effective quarter, 1Q21 to 4Q26. Gaps mean the code was not in that quarter’s file, or CMS gave no payment limit.From the 4Q26 NDC–HCPCS crosswalk. “Limit / pkg” is the 4Q26 payment limit times the billing units in one package.
| Product | Labeler | NDC | Units / pkg | Limit / pkg |
|---|---|---|---|---|
| Piperacillin And Tazobactam | Pfizer Inc | 00409-3390-10 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | B. Braun Medical Inc. | 00264-3446-11 | 48 | $56.784 |
| Piperacillin Sodium-Tazobactam Sodium | B. Braun Medical Inc. | 00264-3448-11 | 72 | $85.176 |
| Piperacillin Sodium-Tazobactam Sodium | B. Braun Medical Inc. | 00264-3450-22 | 96 | $113.568 |
| Piperacillin Sodium-Tazobactam Sodium | Pfizer Inc | 00409-2999-14 | 12 | $14.196 |
| Piperacillin Sodium-Tazobactam Sodium | Pfizer Inc | 00409-3374-02 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Pfizer Inc | 00409-3378-13 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Pfizer Inc | 00409-3379-04 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Pfizer Inc | 00409-3383-02 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Pfizer Inc | 00409-3383-10 | 20 | $23.66 |
| Product | Labeler | NDC | Units / pkg | Limit / pkg |
|---|---|---|---|---|
| Piperacillin Sodium-Tazobactam Sodium | Pfizer Inc | 00409-3385-13 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Pfizer Inc | 00409-3385-15 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Pfizer Inc | 00409-3390-04 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Sandoz Inc. | 00781-3110-95 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Sandoz Inc. | 00781-3113-95 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Sandoz Inc. | 00781-3114-95 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Sandoz Inc. | 00781-3180-94 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | Sandoz Inc. | 00781-9210-95 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Sandoz Inc. | 00781-9213-95 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Sandoz Inc. | 00781-9214-95 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Sagent Pharmaceuticals | 25021-0164-30 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Sagent Pharmaceuticals | 25021-0165-30 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Sagent Pharmaceuticals | 25021-0166-48 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Sagent Pharmaceuticals | 25021-0181-99 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | WG Critical Care, LLC | 44567-0801-10 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | WG Critical Care, LLC | 44567-0802-10 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | WG Critical Care, LLC | 44567-0803-10 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | WG Critical Care, LLC | 44567-0804-01 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | Eugia US LLC | 55150-0119-30 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Eugia US LLC | 55150-0120-30 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Eugia US LLC | 55150-0121-50 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Apotex Corp | 60505-6156-04 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Apotex Corp | 60505-6157-04 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Apotex Corp | 60505-6159-04 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Apotex Corp | 60505-6262-00 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | Apollo Pharmaceuticals Inc. | 61990-0110-02 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Apollo Pharmaceuticals Inc. | 61990-0120-02 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Apollo Pharmaceuticals Inc. | 61990-0130-02 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Apollo Pharmaceuticals Inc. | 61990-0150-01 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 63323-0981-21 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 63323-0981-53 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 63323-0983-21 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 63323-0983-53 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 65219-0256-00 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 65219-0256-24 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 65219-0256-28 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 65219-0259-45 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 65219-0259-55 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 65219-0434-20 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | FreseniUS Kabi USA, LLC | 65219-0436-20 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Piramal Critical Care Inc | 66794-0216-41 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Piramal Critical Care Inc | 66794-0217-41 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Piramal Critical Care Inc | 66794-0218-41 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | BluePoint Laboratories | 68001-0506-30 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | BluePoint Laboratories | 68001-0507-82 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | BluePoint Laboratories | 68001-0508-31 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Athenex Pharmaceutical Division, LLC | 70860-0120-20 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Athenex Pharmaceutical Division, LLC | 70860-0121-30 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Athenex Pharmaceutical Division, LLC | 70860-0122-50 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Athenex Pharmaceutical Division, LLC | 70860-0123-99 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | Armas Pharmaceuticals Inc. | 72485-0403-10 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Armas Pharmaceuticals Inc. | 72485-0404-10 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Civica, Inc. | 72572-0414-10 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Civica, Inc. | 72572-0418-10 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Civica, Inc. | 72572-0573-10 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Civica, Inc. | 72572-0574-10 | 40 | $47.32 |
| Piperacillin Sodium-Tazobactam Sodium | Apollo Pharmaceuticals | 81284-0151-10 | 20 | $23.66 |
| Piperacillin Sodium-Tazobactam Sodium | Apollo Pharmaceuticals | 81284-0152-10 | 30 | $35.49 |
| Piperacillin Sodium-Tazobactam Sodium | Apollo Pharmaceuticals | 81284-0154-01 | 12 | $14.196 |
| Piperacillin Sodium-Tazobactam Sodium | Apollo Pharmaceuticals | 81284-0155-01 | 36 | $42.588 |
| Piperacillin Sodium-Tazobactam Sodium | Avenacy Inc. | 83634-0106-50 | 40 | $47.32 |
| Piperacillin Sodium/Tazobactam Sodium | Apollo Pharmaceuticals | 81284-0153-10 | 40 | $47.32 |
| Zosyn | Baxter Healthcare Corporation | 00338-9632-24 | 48 | $56.784 |
| Zosyn | Baxter Healthcare Corporation | 00338-9636-24 | 72 | $85.176 |
| Zosyn | Baxter Healthcare Corporation | 00338-9638-12 | 48 | $56.784 |
| Quarter | Payment limit | Change | Billing unit | Description | Source file |
|---|---|---|---|---|---|
| 4Q26 | $1.183 | −$0.035 | 1.125 GM | Piperacillin/tazobactam | v1, posted September 17, 2026 |
| 3Q26 | $1.218 | +$0.133 | 1.125 GM | Piperacillin/tazobactam | v1, posted September 15, 2026 |
| 2Q26 | $1.085 | −$0.006 | 1.125 GM | Piperacillin/tazobactam | v1, posted September 15, 2026 |
| 1Q26 | $1.091 | +$0.02 | 1.125 GM | Piperacillin/tazobactam | v1, posted September 15, 2026 |
| 4Q25 | $1.071 | −$0.037 | 1.125 GM | Piperacillin/tazobactam | v1, posted September 8, 2026 |
| 3Q25 | $1.108 | −$0.011 | 1.125 GM | Piperacillin/tazobactam | v1, posted March 10, 2026 |
| 2Q25 | $1.119 | −$0.016 | 1.125 GM | Piperacillin/tazobactam | v1, posted March 10, 2026 |
| 1Q25 | $1.135 | +$0.033 | 1.125 GM | Piperacillin/tazobactam | v1, posted December 19, 2025 |
| 4Q24 | $1.102 | −$0.078 | 1.125 GM | Piperacillin/tazobactam | v1, posted June 11, 2025 |
| 3Q24 | $1.18 | +$0.13 | 1.125 GM | Piperacillin/tazobactam | v1, posted June 11, 2025 |
| 2Q24 | $1.05 | −$0.127 | 1.125 GM | Piperacillin/tazobactam | v1, posted March 11, 2025 |
| 1Q24 | $1.177 | +$0.291 | 1.125 GM | Piperacillin/tazobactam | v1, posted December 19, 2024 |
| 4Q23 | $0.886 | −$0.473 | 1.125 GM | Piperacillin/tazobactam | v1, posted October 10, 2024 |
| 3Q23 | $1.359 | +$0.023 | 1.125 GM | Piperacillin/tazobactam | v1, posted June 5, 2024 |
| 2Q23 | $1.336 | −$0.187 | 1.125 GM | Piperacillin/tazobactam | v1, posted February 23, 2024 |
| 1Q23 | $1.523 | +$0.044 | 1.125 GM | Piperacillin/tazobactam | v1, posted December 6, 2023 |
| 4Q22 | $1.479 | +$0.195 | 1.125 GM | Piperacillin/tazobactam | v1, posted June 22, 2023 |
| 3Q22 | $1.284 | −$0.068 | 1.125 GM | Piperacillin/tazobactam | v1, posted June 9, 2023 |
| 2Q22 | $1.352 | −$0.064 | 1.125 GM | Piperacillin/tazobactam | v1, posted December 14, 2022 |
| 1Q22 | $1.416 | −$0.061 | 1.125 GM | Piperacillin/tazobactam | v1, posted June 8, 2022 |
| 4Q21 | $1.477 | +$0.059 | 1.125 GM | Piperacillin/tazobactam | v1, posted June 2, 2022 |
| 3Q21 | $1.418 | −$0.09 | 1.125 GM | Piperacillin/tazobactam | v1, posted June 2, 2022 |
| 2Q21 | $1.508 | −$0.103 | 1.125 GM | Piperacillin/tazobactam | v1, posted March 1, 2022 |
| 1Q21 | $1.611 | – | 1.125 GM | Piperacillin/tazobactam | v1, posted December 10, 2021 |
“Change” is the difference from the previous quarter, shown only when both quarters have a payment limit and the billing unit is the same. “vs. last quarter” and “vs. a year ago” follow the same rule.
